Leukemia

The Role of Mutations in Epigenetic Regulators in Myeloid Malignancies

Nature Reviews Cancer 2012 paper on the role of epigenetic regulator mutations in myeloid malignancies (AML, MDS, MPN) — summarizing how mutations in DNMT3A, TET2, IDH1/2, EZH2, and others alter the cancer epigenome. A key reference from the early next-generation sequencing era of cancer genomics.